As an experienced medicinal chemist, I provide specialized consulting services to support drug discovery and development efforts. With a deep understanding of molecular design, synthesis, and optimization, I help researchers, pharmaceutical companies, and biotech startups navigate the complexities of bringing innovative therapeutics from concept to reality.
High-throughput screening (HTS) is a vital step in drug discovery, enabling the rapid identification of active compounds from large chemical libraries. I assist in designing, analyzing, and interpreting HTS data to ensure the selection of promising candidates.
Hit Identification (Hit ID)
Finding the right starting point for drug development is critical. I support hit identification through screening methodologies, compound selection strategies, and preliminary structure-activity relationship (SAR) studies to validate hits.
Hit-to-Lead Optimization (H2L)
Transitioning from hit compounds to viable lead candidates requires careful modification and assessment. I guide the optimization process, improving potency, selectivity, and physicochemical properties while addressing potential liabilities.
Lead Optimization (LO)
Refining lead compounds into clinical candidates involves a multidisciplinary approach. I offer expertise in optimizing drug-like properties, ADME (absorption, distribution, metabolism, and excretion) profiles, and reducing off-target effects to enhance therapeutic potential.
